New Catalytic Concepts for the Asymmetric Aldol Reaction
نویسندگان
چکیده
Mukaiyama s classic catalytic asymmetric aldol reaction with enolsilanes has been improved upon over the years; now new approaches to the reaction have been developed. Those reviewed here are the use of new transition metal based catalysts for the aldol reaction using silyl enolates, the use of other O-silylated nucleophiles, tin-modified or even unmodified ketones as substrates, and the use of chiral nonmetallic Lewis acids or Lewis bases as catalysts.
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